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WPVI-TV Report on Cotara/GBM Patient 5-20-07 What is this ?

 
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cjgaddy
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Joined: 12 Oct 2005
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PostPosted: Wed May 23, 2007 12:54 pm    Post subject: WPVI-TV Report on Cotara/GBM Patient 5-20-07 Reply with quote

Encouraging 5-20-07 Philadelphia TV news report about the 1st NABTT Cotara/GBM Ph.1 trial patient, Phil Marfuta (Princeton Grad. Student), who was treated in Nov. 2006 at UPENN by Dr. Kevin Judy:

WPVI-TV CH 6 (ABC), PHILADELPHIA
5/20/07: “Drug In Real Life Action” [Cotara, NABTT, Dr. Kevin Judy/UPENN, Marfuta]
Reporter: Anita Brickman - ACTION NEWS HealthCheck
Go to #13 in this link:
http://media.vmsnews.com/MonitoringReports/052107/726150/H001044408

[WPVI-TV CC] Brain Cancer is a devastating diagnosis to hear. For Phil Marfuta, bad headaches were the 1st clue that something was wrong… I was under stress at work. So I wasn't sleeping. Reporter: this Princeton grad student was told he had tension headaches and pain relievers should the trick and it didn't work. Phil: I was writing an email to somebody and it came out garbled. Reporter: After a CT scan of the head, Phil got awful news. Phil: There is something about 6 cm in size that’s in your head. Reporter: That golf ball sized growth was glioblastoma [“GBM”], a very aggressive cancer that roots itself into the brain. Dr. Judy: There are tumor cells interspersed throughout the normal brain, for several centimeters around the tumor. Reporter: Neither radiation nor standard chemo can stop glioblastoma. Dr. Kevin Judy, of the hosp. of UPENN, is helping to test a new approach, a drug called Cotara. Cotara is a radioactive isotope, a sort of liquid radiation, that is implanted in the skull. Dr. Judy: The antibody attaches itself directly to a component of the tumor cell. Reporter: there it delivers its toxic payload in Tumor Necrosis Therapy, TNT, just like the explosive. Dr. Judy: We seem to be keeping the tumor in check. Reporter: trials are in the 2nd of 3 phases. While it's not a cure, it may give patients more time and that's big progress this type of cancer. *end*

Recall these 2 prev. articles:
A. 3-8-07: “Grad Student [Phil (Marfuta) Bannister] Tries New Cancer Drug”
Welcome to NCSU
… By Peter Wei, Princetonian Staff Writer
http://www.dailyprincetonian.com/archives/2007/03/08/news/17638.shtml
B. 2-22-07: “New Clinical Trial for Deadly Brain Tumors”
…UPenn Medicine Article. Feb. 22, 2007
http://www.uphs.upenn.edu/news/News_Releases/feb07/brain-tumor-trial.html

Note: Phil posts as ‘Phil from NJ’ on the Young Adults Surviving Glioblastoma (YASG) forum: http://www.yasg.com
His latest post:
Apr 19, 2007 12:30pm Re: Please update
Still stable, hanging in there. Still not cured, still not worse. I guess you guys know how it goes.
http://pub39.bravenet.com/forum/3310316029/show/625454
Other posts by Phil:
Feb07: http://pub39.bravenet.com/forum/3310316029/show/604367
Jan07: http://pub39.bravenet.com/forum/3310316029/show/597051
Jan07: http://pub39.bravenet.com/forum/3310316029/show/591352
Dec06: http://pub39.bravenet.com/forum/3310316029/show/585238 **
Nov06: http://pub39.bravenet.com/forum/3310316029/show/579224
Oct06: http://pub39.bravenet.com/forum/3310316029/show/574991
Aug06: http://pub39.bravenet.com/forum/3310316029/show/558483

ClinicalTrials.gov:
“Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients with Progressive or Recurrent Glioblastoma Multiforme”
This study is currently recruiting patients.
http://www.clinicaltrials.gov/ct/show/NCT00128635

= = = = = = = = FYI:
The Jerod Swan & Freddie Sanford Cotara/GBM success stories:
I. The Jerod Swan Cotara/Brain Success Story (8 years survival):
4-19-02: JEROD SWAN, PATIENT: “EVERYTHING I AM AND ALL I DO NOW IS BECAUSE OF IT YOU KNOW - AND I'M JUST VERY THANKFUL TO BE ALIVE.”
6-16-06 update: “The good news is that as of today, Jerod is doing very well… living in xxxxx. From all appearances, the TNT drug approach to his cancer worked.”
http://web.ksl.com/dump/news/cc/uthealth/tumor.htm
II. The Freddie Sanford Cotara/Brain Success Story (6 years survival):
6-5-05: “He was one of 51 patients to be treated over the past 7 years at MUSC in a study with a "convection-enhanced delivery" of a drug called Cotara… 3.5 years later, at 46, Sanford's still alive, making him a member of a very small group.”
6-5-2005: “I think you've beat the cancer,” Dr. Sunil Patel of MUSC told him. Freddie Sanford already has passed the 5-yr threshold, and scans of his brain show there's no tumor left, following treatment by a drug called Cotara.”
6-16-06 update: “Sanford still alive and doing very very well indeed!!”
http://archives.postandcourier.com/archive/arch05/0605/arc06172381169.shtml
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