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ladyjanegray New User
Joined: 06 Nov 2007 Posts: 1
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Posted: Tue Nov 06, 2007 9:35 pm Post subject: Help! BIRADS 4 20% or 25-50% chance of cancer? |
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I have just been advised to have a biopsy for BIRADS 4 cluster microcalcification. Why is it that some sites (namely johns hopkins) say the chances of cancer in this case is 20% and other sites say 25-50%. It is very confusing as one puts the risk quite low and the other quite high. Also 25-50% is such a wide range - why is this?
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brainman Site Admin

Joined: 13 Oct 2005 Posts: 3454 Location: Tennessee
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Posted: Tue Nov 06, 2007 10:17 pm Post subject: Re: Help! BIRADS 4 20% or 25-50% chance of cancer? |
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Maybe they are reporting results from different studies. The range looks like it may have come for a compilation of reviews of medical journals. Yes, it is a wide range. That just shows how much uncertainty the research still has.
Best wishes. _________________ Jim
Site Administrator and long-term cancer survivor
1992 Astrocytoma grade 2, left motor strip
2005 Recurrence this time said to be an Oligodendoglioma grade 3, same location.
My Story Part 1: http://cancerforums.net/viewtopic.php?p=7350
My Story Part 2: http://cancerforums.net/viewtopic.php?t=8029
Blog http://jimhawkinsport.blogspot.com/ |
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Muttsmom Senior User

Joined: 30 Sep 2004 Posts: 631 Location: Northern AL
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Posted: Tue Nov 06, 2007 11:33 pm Post subject: Re: Help! BIRADS 4 20% or 25-50% chance of cancer? |
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I agree with Jim. There is so much uncertainty when it comes to this disease.
I'm a firm believer in biopsies since I was told I was fine and come back in a year when the mammogram and ultra sound didn't find the lump that me and the doctor could feel and I ended up Stage III BC. Also, since it's the only way to know for sure, peace of mind if it's B9 and if it is cancer, catch it early.
Let us know and try not to look at stats. Stats are numbers and we are people. They do studies and they have to use stats based on their findings. _________________ Nancy
2/14/02 ILC 43 - 5.5 cm 9+/16 nodes
Stage IIIA er/pr+ Her2-
2/02 MRM
FECx6 radsx33
Tamoxifen - Arimidex (chemo induced menopause)
4/03 SM w/bilat. recon.
9/03 expanders removed
5/04 repair reconst. disaster
10/04 Actonel for bone/joint pain from Arimidex
NED - 5 years
3/07 Diabetes
In memory of Kim 12/1/04 |
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bluephoenixx New User
Joined: 10 Jul 2007 Posts: 9
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Posted: Wed Dec 12, 2007 1:18 pm Post subject: Re: Help! BIRADS 4 20% or 25-50% chance of cancer? |
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I went through this, too. It's hard give an actual percentage because different facilities can have different rates of false positives and the numbers of those whose mammograms actually turn up malignant after biopsy. Mine was a BIRAD 4 and biopsy was strongly advised, but that was mostly due to the fact that it was my first mammogram in eight years (after one in my 30's to check for what turned out to be a simple cyst).
BTW, my biopsy and cyst contents both turned out benign.
If a stereotaxic biopsy can be done and you've had more than one professional opinion on the mammogram, combined with a good history and taking other exam findings into consideration, it might not be a bad idea -- just to be sure what you're dealing with. On microcalcifications, know that many things can contribute to them, not just cancer. But if it IS cancer, the sooner you know, the better! (That said, I do think many radiologists and surgeons are scared to death of missing a cancer for fear of lawsuits and so end up erring on the side of medical paranoia, but it's still YOUR health and life we're talking about.)
Good luck, continue educating yourself, but don't sweat it too much. There's lots of help and information out there either way. Take care.
Gail |
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